| Date | Opponets | Result |
| 8th Sept 00 | vs Lija Ath | 8-2 |
| 7th Oct 00 | vs Mosta | 2-2 |
| 22nd Oct 00 | vs St Andrew's | 1-2 |
| 11th Nov 00 | vs Marsa | 2-4 |
| 18th Nov 00 | vs Tarxien R. | 2-5 |
| 2nd Dec 00 | vs St Patrick | 1-1 |
| 8th Dec 00 | vs Zurrieq | 0-2 |
| 16th Dec 00 | vs Qormi | 0-2 |
| 13th Jan 01 | vs Lija Ath | 3-0 |
| 27th Jan 01 | vs Mosta | 0-8 |
| 10th Feb 01 | vs Tarxien R. | 0-3 |
| 17th Feb 01 | vs St Andrew's | 1-1 |
| 4th Mar 01 | vs St Patrick | 1-4 |
| 18th Mar 01 | vs Marsa | 2-2 |
| 25th Mar 01 | vs Zurrieq | 0-1 |
| 8th Apr 01 | vs Qormi | 0-4 |
| Reserves Sec B | P | W | D | L | F | A | Pts |
| Mosta F.C. | 16 | 12 | 3 | 1 | 48 | 10 | 39 |
| St Patrick F.C. | 16 | 12 | 1 | 3 | 58 | 14 | 37 |
| Qormi F.C. | 16 | 11 | 2 | 3 | 40 | 18 | 35 |
| Zurrieq F.C. | 16 | 7 | 4 | 5 | 24 | 21 | 25 |
| St Andrews F.C. | 16 | 7 | 2 | 7 | 33 | 28 | 23 |
| Tarxien R F.C. | 16 | 5 | 3 | 8 | 32 | 26 | 18 |
| Marsa F.C. | 16 | 3 | 4 | 9 | 25 | 50 | 13 |
| MARSAXLOKK F.C. | 16 | 2 | 4 | 10 | 23 | 43 | 10 |
| Lija Ath F.C. | 16 | 1 | 1 | 14 | 14 | 87 | 4 |